Aerobic Metabolism

Metabolism that utilizes oxygen is called aerobic metabolism.

Energy production through oxygenation (with oxygen) yielding 32 ATP molecules from the interaction of one glucose and one oxygen molecule. “Paramount in importance, though, is the continuous flow of oxygenated blood. This flow is central to metabolism, the production of energy and other materials necessary for life. Energy production is synonymous with life. No energy…no life. Blood delivers oxygen and glucose to the tissues. One molecule of glucose is oxidized in the cell’s mitochondria to produce 36 adenosine triphosphate molecules (ATP).

O2 + Glucose = H2O + CO2 ===> 36 ATP

Metabolism that utilizes oxygen is called aerobic metabolism. The above equation is the balance of the much abbreviated Kreb’s cycle. Any unsettled memories bubbling up? The point is that oxygen when combined with glucose produces a substantial amount of energy.

Note that ATP is the primary energy molecule for the body. Virtually every activity – thinking, movement, cardiac contraction, protein formation, etc. – requires ATP. Without a continuos production of ATP, each of these processes would cease.

Aerobic metabolism has by-products of water (H2O) and carbon dioxide (CO2). Water we can definitely use. In fact, about 2/5 of body fluids come from aerobic metabolism, from what is burned (or oxidized) rather than what is drank. And carbon dioxide is readily breathed off at about 20 times the rate that oxygen diffuses into the bloodstream. Aerobic metabolism is incredibly efficient and effective.

Sufficient cardiac output is necessary to deliver adequate supplies of oxygen and nutrients (glucose) to the tissues. This translates to the conclusion that cardiac output is directly related to energy production. Low cardiac output will reduce energy levels.

For example, if your cardiac output fell to 3500 ml (about 2/3 of normal) your oxygen – and hence your energy supply – would be decreased as well. Your brain with 1/3 less energy may be less sharp, confused or even unconscious. Your muscles with 1/3 less energy would feel weaker. In contrast, high cardiac output satisfies periods of high energy demand.

Aerobic and Anaerobic Metabolism

1. Six Second ECG Guidebook (2012), T Barill, p. 25-26, 189

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