Anaerobic Metabolism

Energy production without oxygen with only 2 ATP produced as well as lactic and pyruvic acid.

When energy demands surpass the supply of vital energy precursors such as oxygen, cells are left with the much less efficient anaerobic energy production – metabolism without oxygen. An insufficient supply of oxygen can occur due to hypoxia, obstructed blood vessels, anemia or low cardiac output conditions.

Anaerobic metabolism is not an efficient energy producer.

O2 + Glucose = LACTIC ACID ===> ONLY 2 ATP

Aerobic metabolism is clearly superior to anaerobic metabolism with regards to energy production. Anaerobic metabolism yields only 2 ATP. Also the production of acid (lactic acid) can alter the acid-base balance and hamper several vital intercellular chemical reactions.

Anaerobic metabolism can buy some time for activities that occur sporadically (i.e. sprinting or weight lifting). Anaerobic metabolism does not produce enough ATP to sustain the viability of cells that are engaged in rhythmic or continuos activity (i.e. myocardial cells).

We have all experienced the effects of anaerobic metabolism after over-engaging in a strenuous activity. The next day our muscles are painful. No, not stairs! Our blood vessels simply delivered insufficient amounts of oxygen and nutrients to satisfy the needs of these muscles. The muscles turned to anaerobic metabolism to boost the ATP supply. As a result, lactic acid accumulated in our tissues.

Aerobic and Anaerobic Metabolism

1. Six Second ECG Guidebook (2012), T Barill, p. 26-27, 189

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Dynamic ECG rhythm interpretation
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