Cardiac Cycle

A complete cardiac cycle occurs with each audible ‘lub-dub’ that is heard with a stethoscope. During this heartbeat, both atria simultaneously contract followed soon after by the contraction of the ventricles. Systole is the contractile phase of each chamber while diastole is the relaxation phase. During the cardiac cycle, the atria and the ventricles each have periods of both systole and diastole.

The purpose of the cardiac cycle is to effectively pump blood. The right heart delivers deoxygenated blood to the lungs. Here oxygen is picked up and carbon dioxide is breathed off. The left heart delivers oxygenated blood to the body. Normally, the volume of blood ejected by the right ventricle to the lungs is about the same as the volume ejected by the left ventricle. A mismatch in volumes ejected by the ventricles (i.e. right ventricle pumps more blood than the left ventricle) can result in heart failure.

The synchronized actions of the atria and the ventricles are coordinated to maximize pumping efficiency. Rhythm disturbances can greatly impair this synchrony, resulting in a less effective cardiac cycle. For simplicity, we’ll consider the events that lead to the ejection of blood from the right ventricle into the lungs beginning at the end of atrial diastole. These events mirror those of the left heart.

The tricuspid valve closes during ventricular systole – otherwise, it remains open. At the end of atrial diastole and ventricular diastole, an open tricuspid valve provides a channel between the right atrium and the right ventricle. As a result, blood flows into both the right atrium and the right ventricle simultaneously. The ventricle receives up to 85% of its blood volume during this period.

Prior to ventricular systole, the atrium contracts. Since the atrium is about 1/3 the size of the ventricle, an atrial contraction only contributes an additional 15-35% of blood volume to the ventricle. This ‘topping up’ of the ventricle by the atrium is called atrial kick. Note that the conclusion of atrial systole coincides with the end of ventricular diastole.

Atrial kick occurs as the atria contract prior to ventricular contraction. Atrial kick contributes 15-35% to the volume of blood in the ventricle. This extra volume in turn increases cardiac output by a similar 15-35%. Note: as we age, atrial kick tends to be a more significant contributor to cardiac output (closer to 35%). This is one reason that our older patients are more affected by rhythm disturbances, such as atrial fibrillation (a quivering of the atria rather than a coordinated contraction), than our younger patients. Atrial fibrillation causes a complete loss of atrial kick.

After ventricular end-diastole, the ventricle enters systole and contracts forcefully. As the pressure within the ventricle increases, the tricuspid valve closes to ensure forward blood flow. Very soon after, the pulmonic valve opens as pressure within the ventricle becomes greater than pulmonary artery pressure. Blood is then ejected into the pulmonary arteries.

As blood is ejected, ventricular pressure falls. When ventricular pressure is below the pulmonary artery pressure, the pulmonic valve closes to prevent back flow of blood into the right ventricle. The closure of the AV valves (tricuspid and mitral valves) normally produces the S1 heart sound. The closure of the semilunar valves (pulmonic and aortic valves) produces the S2 heart sound.

While ventricular systole ejects blood into either the pulmonary or vascular systems, ventricular diastole is at least as important. Without a sufficient period of diastole, systole is ineffective. During diastole, the ventricles relax. But in relaxing, the ventricles open to regain their pre-contractile size, effectively dropping the chamber pressure below that of the vena cava. As a result, blood is drawn into the ventricle during ventricular (and atrial) diastole. Then the cardiac cycle begins again.

Figure 2.1 Route of Blood Flow Through the Heart

De-oxygenated blood enters the right side of the heart via the vena cava and is ejected through to the lungs where oxygen is replenished and carbon dioxide diffuses out to the lungs. Oxygenated blood enters the left side of the heart and is subsequently delivered to the body.

1. Six Second ECG Guidebook (2012), T Barill, p. 22-23

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