Stroke Volume

The amount of blood ejected by either the right or left ventricle with one beat (contraction).

While heart rate is an undisputed contributor to cardiac output, stroke volume is the other major player. As heart rates vary to changes in cardiac output demand, so does stroke volume. Stroke volume – the amount of blood ejected with each beat – fluctuates with changes in preload, afterload, and catecholamine release.

Preload

The blood supply to the ventricle is often referred to as preload. Technically, the definition of preload is the volume or pressure in the ventricle at the end of diastole. Note that atrial kick offers much to preload, especially for those getting on in years (contributing up to 35% of cardiac output). Preload is connected to stroke volume and cardiac output via the Frank-Starling law.

Afterload

The resistance to the ejection of blood by the ventricle is called afterload. The left ventricle, for example, must create sufficient pressures during systole to overcome diastolic arterial pressure and systemic vascular resistance before any blood is ejected. While preload enhances contractility and stroke volume, high pressures in the arterial vessels during ventricular end diastole is inversely related to stroke volume.

See also:

Ejection Fraction

Frank-Starling’s Law

1. Six Second ECG Guidebook (2012), T Barill, p. 32

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