ST Depression

The downward placement of the ST segment greater than 1 mm from the isoelectric line; suggestive of cardiac ischemia, but also may point to ventricular hypertrophy, digoxin use, and pericarditis among other possibilities.

Between the QRS complex and the T wave, lies the ST segment. The ST segment usually follows the isoelectric line. The ST segment represents early repolarization of the ventricles. Early repolarization includes a plateau phase where the cardiac cell membrane potential does not change.

During early repolarization, the positive ion potassium exits the cardiac cell while the positive ion calcium enters the cardiac cell, effectively negating any change in cell membrane potential. Because the cell membrane does not change its electrical potential, ECG leads do not record any electrical activity. As a result, the ST segment usually lies along the ECG baseline.

Determining where the ST segment begins is determined by the J point. The J point, the juncture of the QRS and the ST segment, defines the starting point of the ST segment. The J point marks where the QRS complex changes direction, forming a notch or bump in the ECG tracing. The ST segment is evaluated for any deviation from the ECG baseline 0.04 seconds (1 mm) after the J point.

While ST deviations may be a normal occurrence for a subset of the population, most often ST deviation is a sign of either myocardial ischemia, myocardial infarction and/or cardiac disease. It makes sense, then, to report any finding of ST deviation from baseline in the ECG interpretation i.e. sinus rhythm with ST depression.

ST depression of 1 mm or more in 2 contiguous leads (neighboring leads) is suggestive of myocardial ischemia, injury or infarction. ST elevation of 1 mm or more in 2 contiguous leads is highly suggestive of a myocardial injury or infarction. Note that ST changes (elevation or depression) are highly suggestive of current events – the acute coronary events are happening now.

The shape of the ST segment, if depressed, bears mention. The depressed ST segment often presents horizontal (see the center QRS complex of Figure 4.17), sloping downwards or sloping upwards. Although all morphologies can indicate myocardial ischemia, the horizontal and downward sloping depressed ST segments are the more likely morphologies that point to ischemic events.

Note that ST changes can occur from conditions other than myocardial ischemia. As mentioned, ST elevation and depression may be a benign finding, although uncommon. For example, ST depression that is concave in shape – called a dig dip – can occur for patients taking digitalis (see Figure 4.17) even at normal blood levels. A depressed and upward sloping ST segment can represent ventricular hypertrophy.

ST segment elevation is a common finding in young healthy adults of African descent. This phenomenon is attributable to normal early repolarization and not a result of cardiac disease. Using an ECG to diagnose a disease state in the absence of direct contact with the patient, a patient’s clinical history and presentation is fraught with peril.

The presence of ST elevation in most views of a 12 lead ECG suggests pericarditis. Ventricular rhythms and supraventricular rhythms with left bundle branch block have wide and bizarre QRS complexes, making the detection of ST changes all but impossible.

Several conditions not linked to cardiac ischemia can produce ST changes. The bottom line: most ST changes indicate cardiac ischemia, requiring urgent treatment BUT every ECG interpretation is more robust when integrated with a patient’s clinical status and history.

Figure 4.13 The QRS Complex, ST Segment and the T Wave | Figure 4.17 ST Segment Deviations

Figure 4.13 depicts the component parts of the QRS complex. The QRS complex consists of a series of waves, the ‘Q’, ‘R’, and ‘S’ waves. The ‘Q’ wave is the first negative deflection from baseline. The ‘R’ wave is the first positive deflection above baseline. The ‘S’ wave follows the ‘R’ wave with a negative deflection. A QRS complex may or may not have all three waveforms. The ST segment begins at the J point and continues to the beginning of the T wave.

Figure 4.17 presents three examples of ST deviation. A digoxin dip is also called a “dig dip”.

1. Six Second ECG Guidebook (2012), T Barill, p. 86-88, 204

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Dynamic ECG rhythm interpretation
Static ECG rhythm interpretation
Clinical Impact Mapping
Acute Coronary Syndromes Overview
Acute Coronary Syndromes In-Depth
ST Segment & T Wave Differential
Identify Bundle Branch Blocks
15 | 18 Lead View Mapping
Electrical Axis
R Wave Progression
Left Bundle Branch Blocks with ACS
Atypical Findings
Acute Non-Ischemic Disease Conditions
Special Cases

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